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KL101

CRY1 Stabilizer

KL101 is a selective stabilizer of cryptochrome 1 (CRY1) that modulates the circadian clock. By stabilizing the CRY1 protein, KL101 enhances its interaction with the core components of the circadian feedback loop, thereby influencing the regulation of circadian rhythms in mammals. This compound is valuable for research into circadian biology and potential therapeutic applications related to circadian rhythm disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Stabilizer
CAS Number	396721-89-4
Applications	CRY1 Stabilizer
Formula	C₂₂H₂₃N₃OS
Molecular Weight	377.50
SMILES	O=C(NC1=C2C(CSC2)=NN1C3=CC=C(C)C=C3C)C4=CC=C(C)C(C)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.