Fig. 1 · Structure
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KL201
CRY1 Stabilizer
KL201 is an isoform-selective stabilizer of cryptochrome 1 (CRY1), functioning as a modulator of the circadian clock. This compound enhances the stability of CRY1 without impacting CRY2, thereby effectively prolonging the period of circadian rhythms in cellular and tissue models. KL201 is valuable for research applications focused on the mechanisms of circadian regulation and their influence on various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Stabilizer |
| CAS Number | 302939-48-6 |
| Applications | CRY1 Stabilizer |
| Formula | C17H14BrN3OS |
| Molecular Weight | 388.28 |
| SMILES | O=C(NC1=C(C2=C(CCCC2)S3)C3=NC=N1)C4=CC=CC=C4Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.