KLHDC2-IN-1 is a ligand that specifically targets the ubiquitin E3 ligase KLHDC2, exhibiting a dissociation constant (Kd) of 160 nM. This compound facilitates the development of PROTACs, which are designed to induce degradation of BRD4 in cellular environments. Its application in cellular research underscores its potential utility in studying protein degradation mechanisms and therapeutic strategies targeting BRD4-related pathways.
KLHDC2-IN-1 is a ligand that specifically targets the ubiquitin E3 ligase KLHDC2, exhibiting a dissociation constant (Kd) of 160 nM. This compound facilitates the development of PROTACs, which are designed to induce degradation of BRD4 in cellular environments. Its application in cellular research underscores its potential utility in studying protein degradation mechanisms and therapeutic strategies targeting BRD4-related pathways.
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