Fig. 1 · Structure

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KM05382

CDK Inhibitor

KM05382 is a selective inhibitor of cyclin-dependent kinase 9 (CDK9), disrupting its activity and consequently leading to reduced transcription of the GAPDH gene. This compound plays a crucial role in regulating transcriptional control and has potential applications in understanding cell cycle dynamics and cancer research. Its unique mechanism makes it valuable for studies aimed at evaluating CDK9's role in gene expression and related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 882291-64-7
Applications CDK Inhibitor
Formula C20H19ClN2O3S2
Molecular Weight 434.96
SMILES
N#CC(SC(SCCOC(NC1=CC(Cl)=CC=C1)=O)=C23)=C3CC(C)(C)CC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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