KNK437

Catalog No.: A14389

pan-HSP inhibitor

KNK437

KNK437 Chemical Structure

CAS NO. 218924-25-5

KNK437, dose-dependently inhibited the acquisition of thermotolerance and the induction of various HSPs including HSP105, HSP70, and HSP40 in COLO 320DM (human colon carcinoma) cells.

Availability: In stock

Package Price Qty
10 mg
$60.00
50 mg
$250.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KNK437, dose-dependently inhibited the acquisition of thermotolerance and the induction of various HSPs including HSP105, HSP70, and HSP40 in COLO 320DM (human colon carcinoma) cells.
Targets
HSP105 HSP72 HSP40
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.78 mL 203.89 mL 407.78 mL
0.5 mM 8.16 mL 40.78 mL 81.56 mL
1 mM 4.08 mL 20.39 mL 40.78 mL
5 mM 0.82 mL 4.08 mL 8.16 mL

*The above data is based on the productmolecular weight 245.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14389
Actions Inhibitor
M. Wt 245.23
Formula C13H11NO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 218924-25-5
Synonyms KNK-437, KNK 437
SMILES O=CN1C(/C(CC1)=C\C2=CC=C(OCO3)C3=C2)=O

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