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$0.00 Biological Activity
KNK437, dose-dependently inhibited the acquisition of thermotolerance and the induction of various HSPs including HSP105, HSP70, and HSP40 in COLO 320DM (human colon carcinoma) cells.
Targets
| HSP105 | HSP72 | HSP40 | ||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.78 mL | 203.89 mL | 407.78 mL |
| 0.5 mM | 8.16 mL | 40.78 mL | 81.56 mL |
| 1 mM | 4.08 mL | 20.39 mL | 40.78 mL |
| 5 mM | 0.82 mL | 4.08 mL | 8.16 mL |
*The above data is based on the productmolecular weight 245.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14389 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 245.23 |
| Formula | C13H11NO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 218924-25-5 |
| Synonyms | KNK-437, KNK 437 |
| SMILES | O=CN1C(/C(CC1)=C\C2=CC=C(OCO3)C3=C2)=O |
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