Kobe2602

Catalog No.: A12578

Ras–Raf inhibitor

Kobe2602

Kobe2602 Chemical Structure

CAS NO. 454453-49-7

Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.

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10 mg
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50 mg
$80.00
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Biological Activity

Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.
In vitro DMSO 79 mg/mL (188.4 mM)
Water Insoluble
Ethanol 38 mg/mL (90.62 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.85 mL 119.24 mL 238.49 mL
0.5 mM 4.77 mL 23.85 mL 47.7 mL
1 mM 2.38 mL 11.92 mL 23.85 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12578
Actions Inhibitor
CAS No. 454453-49-7
Formula C14H9F4N5O4S
M. Wt 419.31
Purity >98%
Synonyms Kobe-2602
SMILES C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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