Total item
Cart Subtotal
$0.00 Biological Activity
Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.
| In vitro | DMSO | 79 mg/mL (188.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 38 mg/mL (90.62 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.85 mL | 119.24 mL | 238.49 mL |
| 0.5 mM | 4.77 mL | 23.85 mL | 47.7 mL |
| 1 mM | 2.38 mL | 11.92 mL | 23.85 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
*The above data is based on the productmolecular weight 419.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12578 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 454453-49-7 |
| Formula | C14H9F4N5O4S |
| M. Wt | 419.31 |
| Purity | >98% |
| Synonyms | Kobe-2602 |
| SMILES | C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an ora…
Balamapimod (MKI-833)
Balamapimod, also known as MKI-822, is a Ras/Raf/MEK inhibitor.
ZM 336372
ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activatio…
Dabigatran ethyl ester
Dabigatran ethyl ester, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.
Diazepinomicin
Diazepinomicin, also known as TLN-4601, is a small-molecule inhibitor of the RAS/RAF/MAPK signaling pathway with potential antineoplastic ac…
AZ628
AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
B-Raf-inhibitor 1
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respec…
MLN2480 (BIIB-024)
MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.
Keywords:buy Kobe2602 | Kobe2602 Supplier | purchase | cost | manufacturer | order | distributor | buy 454453-49-7| 454453-49-7 Supplier | purchase 454453-49-7 | 454453-49-7 cost | 454453-49-7 manufacturer | order 454453-49-7 | 454453-49-7 distributor
Adooq Quality Guarantee
We promise all products perform as described.