KPT 335
Catalog No.: A16078
SINE inhibitor
KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).
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Research use only. We do not sell to patients.
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Biological Activity
| Description | KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE). | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A16078 |
|---|---|
| Formula | C18H12F6N6O |
| Molecular Weight | 442.32 |
| CAS Number | 1392136-43-4 |
| SMILES | O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2 |
| Synonyms | Verdinexor |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 83 mg/mL (187.65 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 10 mg/mL | ||
| In vivo | 5% DMSO+corn oil | 14 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.61 mL | 113.04 mL | 226.08 mL |
| 0.5 mM | 4.52 mL | 22.61 mL | 45.22 mL |
| 1 mM | 2.26 mL | 11.3 mL | 22.61 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
