KPT 335

Catalog No.: A16078

SINE inhibitor

KPT 335

KPT 335 Chemical Structure

CAS NO. 1392136-43-4

KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$180.00
50 mg
$780.00
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Biological Activity

KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).
Targets
CRM1
In vitro (25°C) DMSO 83 mg/mL (187.65 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL
In vivo 5% DMSO+corn oil 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.04 mL 226.08 mL
0.5 mM 4.52 mL 22.61 mL 45.22 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16078
Actions Inhibitor
CAS No. 1392136-43-4
Formula C18H12F6N6O
M. Wt 442.32
Purity >98%
Synonyms Verdinexor
SMILES O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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