KPT-6566

Name: KPT-6566
Brand: Adooq Bioscience
SKU: A19126
Rating: 5 (288 reviews)

Catalog No.: A19126

prolyl isomerase PIN1 inhibitor

KPT-6566, a potent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domain. Anti-cancer activity.

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KPT-6566 881487-77-0 prolyl isomerase PIN1 inhibitor

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Grouped product items
Size	Price	Stock
1mg	$90.00	In stock
2mg	$140.00	In stock
5mg	$290.00	In stock
10mg	$450.00	In stock
25mg	$745.00	In stock
50mg	$1,055.00	In stock
100mg	$1,425.00	In stock
*10mM 1mL in DMSO**	$280.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	KPT-6566, a potent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domain. Anti-cancer activity.

Product Information

Catalog Num	A19126
Formula	C22H21NO5S2
Molecular Weight	443.54
CAS Number	881487-77-0
SMILES	O=C(O)CSC(C1=O)=C/C(C2=C1C=CC=C2)=N\S(=O)(C3=CC=C(C(C)(C)C)C=C3)=O
Synonyms	KPT 6566; KPT6566
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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