Documents & Downloads

KRAS G12C-IN-72

KRAS G12C Inhibitor

KRAS G12C-IN-72 is a selective inhibitor targeting the KRAS G12C mutant protein. This compound exhibits potent activity against KRAS G12C, making it valuable for cancer research, particularly in therapeutic development. It can also serve as a ligand for synthesizing PROTACs, such as KRAS degrader-1, facilitating innovative approaches in targeted protein degradation studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2326523-41-3
Applications	KRAS G12C Inhibitor
Formula	C₃₁H₃₃ClFN₇O₂
Molecular Weight	590.09
SMILES	ClC1=CC=CC2=C1C(N3CC4=NC(OC[C@@H]5CCCN5)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C4CC3)=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.