KRAS G12C-IN-74

Name: KRAS G12C-IN-74
Brand: Adooq Bioscience
SKU: A63617
Rating: 5 (288 reviews)

Catalog No.: A63617

KRAS G12C Inhibitor

KRAS G12C-IN-74 is a selective inhibitor of KRAS G12C with a target IC50 of 43.18 nM. This compound induces G0/G1 cell cycle arrest and promotes apoptosis specifically in KRAS G12C-mutated cancer cells. It is suitable for research applications focusing on KRAS G12C-driven pancreatic, colorectal, and lung cancers.

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KRAS G12C-IN-74 3085516-79-3 KRAS G12C Inhibitor

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Biological Activity

Description	KRAS G12C-IN-74 is a selective inhibitor of KRAS G12C with a target IC50 of 43.18 nM. This compound induces G0/G1 cell cycle arrest and promotes apoptosis specifically in KRAS G12C-mutated cancer cells. It is suitable for research applications focusing on KRAS G12C-driven pancreatic, colorectal, and lung cancers.

Product Information

Catalog Num	A63617
Formula	C33H38FN7O2S
Molecular Weight	615.76
CAS Number	3085516-79-3
SMILES	O=C(N1[C@H](CN(C2=NC(OCC34N(CCC4)CCC3)=NC5=C2CCN(C5)C6=CC=CC7=C6C(C)=CS7)CC1)CC#N)C(F)=C

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