Fig. 1 · Structure
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KRAS G12C inhibitor 41
Anti-cancer Agent
KRAS G12C inhibitor 41 is a selective inhibitor targeting the KRAS G12C mutant protein, a critical player in oncogenic signaling pathways. This compound demonstrates significant anti-cancer activity, making it a valuable tool for investigating KRAS G12C-mediated malignancies. Its application in research can facilitate the development of targeted therapies aimed at overcoming resistance mechanisms in cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2660014-65-1 |
| Applications | Anti-cancer Agent |
| Formula | C36H37ClFN9O2 |
| Molecular Weight | 682.19 |
| SMILES | CN1CCC[C@H]1COC2=NC(N3C[C@@H](N(CC3)C(C(C4=CN=CN=C4)=C)=O)CC#N)=C5C(CN(C6=CC=CC7=C6C(Cl)=C(F)C=C7)CC5)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.