KRAS G12C inhibitor 61

Name: KRAS G12C inhibitor 61
Brand: Adooq Bioscience
SKU: A36749
Rating: 5 (288 reviews)

Catalog No.: A36749

KRAS G12C Inhibitor

KRAS G12C Inhibitor 61 is a selective inhibitor targeting the KRAS G12C mutation. It effectively inhibits phospho-ERK 1/2 in MIA PaCa-2 cells, exhibiting an IC50 of 9 nM. This compound is valuable for research into pancreatic, colorectal, and lung cancers, contributing to studies focused on therapeutic strategies for KRAS-driven malignancies.

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KRAS G12C inhibitor 61 2300967-40-0 KRAS G12C Inhibitor

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Biological Activity

Description	KRAS G12C Inhibitor 61 is a selective inhibitor targeting the KRAS G12C mutation. It effectively inhibits phospho-ERK 1/2 in MIA PaCa-2 cells, exhibiting an IC50 of 9 nM. This compound is valuable for research into pancreatic, colorectal, and lung cancers, contributing to studies focused on therapeutic strategies for KRAS-driven malignancies.

Product Information

Catalog Num	A36749
Formula	C31H33ClFN7O2
Molecular Weight	590.09
CAS Number	2300967-40-0
SMILES	O=C1N=C(N2[C@@H](C)CN([C@H](C)C2)C(C=C)=O)C3=C(N1C4=C(C)C=CN=C4C(C)C)N=C(C5=C(N)C=CC=C5F)C(Cl)=C3

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