Fig. 1 · Structure
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KRAS G12D inhibitor 13
Anti-cancer Agent
KRAS G12D inhibitor 13 is a selective inhibitor targeting the KRAS G12D mutation, a critical driver in various cancers. This compound effectively disrupts KRAS-mediated signaling pathways, demonstrating potent anti-cancer activity. It serves as a valuable tool for studying the role of KRAS G12D in tumor biology and evaluating potential therapeutic strategies for KRAS-related malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2648552-62-7 |
| Applications | Anti-cancer Agent |
| Formula | C31H33F2N7O3 |
| Molecular Weight | 589.64 |
| SMILES | O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[C@H](C)CN(C([C@H]6NC6)=O)C[C@H]5C)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.