Fig. 1 · Structure

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KRAS inhibitor-34

KRAS Inhibitor

KRAS inhibitor-34 is a selective inhibitor targeting the KRAS protein, exhibiting an IC50 of 6.4 nM. This compound is utilized in tumor research to investigate KRAS-mediated signaling pathways and its role in cancer progression. It provides a valuable tool for studying the therapeutic potential of KRAS inhibition in various malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3054800-66-4
Applications KRAS Inhibitor
Formula C42H39F3N6O3
Molecular Weight 732.79
SMILES
C#CC1=C(C=CC2=CC(O)=CC(C3=C(C4=C(C(N5CCN(CC5)C(/C(F)=C/C6=CC=CC=N6)=O)=NC(OC[C@@]78CCCN([C@@]7(CCC8)[H])C)=N4)C=C3)F)=C21)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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