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KRAS inhibitor-40

KRAS Inhibitor

KRAS inhibitor-40 is a selective inhibitor targeting the KRAS G12C-BRAF complex. By inhibiting ERK phosphorylation within the KRAS downstream signaling pathway, this compound effectively suppresses tumor cell proliferation across various KRAS mutation types. KRAS inhibitor-40 demonstrates notable antitumor activity, making it a valuable tool for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3059496-56-6
Applications	KRAS Inhibitor
Formula	C₅₃H₆₈ClF₄N₉O₈S
Molecular Weight	1102.67
SMILES	O=C([C@H](F)Cl)N1CCC(C(N([C@H](C(N[C@H](C(N2N[C@H](C(OCC(C)(C)CC3=C(C4=C([C@H](C)OC)N=CC(N5CCOCC5)=C4)N6CC(F)(F)C7)=O)CCC2)=O)CC8=NC(C9=CC7C6C3=C9)=CS8)=O)C(C)C)C)=O)(F)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.