Fig. 1 · Structure

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KRH-594

Angiotensin AT1 Receptor Antagonist

KRH-594 is an orally active antagonist of the angiotensin AT1 receptor. It has been shown to mitigate the progression of diabetic nephropathy and hyperlipidemia. Additionally, KRH-594 demonstrates the ability to inhibit cardiac hypertrophy, making it a valuable tool for research in cardiovascular and metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 167006-13-5
Applications Angiotensin AT1 Receptor Antagonist
Formula C25H23N7O3S
Molecular Weight 501.56
SMILES
O=C(C1=C(C(/N=C2SC(CC)=NN\2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=O)CCC1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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