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KRN7000 analog 3

iNKT Agonist

KRN7000 analog 3 is an iNKT agonist targeting invariant natural killer T cells, enhancing immune responses. It has been shown to induce higher levels of IL-2 cytokine secretion (49.2-62.6 ng/mL) compared to α-GalCer (44.1 ng/mL) in mNK1.2 cells. This compound holds potential for applications in antitumor research and as a vaccine adjuvant, facilitating studies aimed at improving immunotherapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1384423-78-2
Applications	iNKT Agonist
Formula	C₄₇H₇₇NO₁₀
Molecular Weight	816.11
SMILES	CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](NC(CCCCCCCCCCC1=CC=C(C=C1)OC2=CC=CC=C2)=O)CO[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.