Fig. 1 · Structure

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KU-2285

Radiosensitizer

KU-2285 is an orally active fluorinated 2-nitroimidazole that functions as a hypoxic cell radiosensitizer. It demonstrates heightened lipophilicity and superior sensitizing activity compared to traditional agents, while exhibiting reduced neurotoxicity. KU-2285 is valuable for research applications focused on tumor diagnosis and enhancing the efficacy of radiotherapy in hypoxic tumor microenvironments.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 121077-11-0
Applications Radiosensitizer
Formula C8H10F2N4O4
Molecular Weight 264.19
SMILES
O=C(NCCO)C(F)(F)CN1C=CN=C1[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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