Fig. 1 · Structure
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Kuraridine
Bioactive Flavonol
Kuraridine is a bioactive flavonol derived from the roots of Sophora flavescens, exhibiting selective inhibition of cGMP-specific phosphodiesterase type 5 (PDE5) with an IC50 of 0.64 μM. This compound demonstrates potential therapeutic applications in the modulation of vascular smooth muscle relaxation and enhancement of nitric oxide signaling. Its unique pharmacological profile makes Kuraridine an interesting candidate for research in cardiovascular and other related biological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 34981-25-4 |
| Applications | Bioactive Flavonol |
| Formula | C26H30O6 |
| Molecular Weight | 438.51 |
| SMILES | O=C(C1=C(OC)C=C(O)C(C[C@H](C(C)=C)C/C=C(C)\C)=C1O)/C=C/C2=CC=C(O)C=C2O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.