Fig. 1 · Structure
Documents & Downloads
Kushenol M
Cat. No.
A69842
CAS
101236-51-5
CYP Inhibitor
Kushenol M is a flavonoid derived from Sophora flavescens, functioning primarily as a cytochrome P450 (CYP) inhibitor. It exhibits potent inhibitory activity, with an IC50 value of 1.29 μM specifically for CYP3A4 in human liver microsomes. This compound is valuable for research involving drug metabolism and pharmacokinetics, as well as studies assessing the interactions and regulation of CYP enzymes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 101236-51-5 |
| Applications | CYP Inhibitor |
| Formula | C30H36O7 |
| Molecular Weight | 508.60 |
| SMILES | C/C(C)=C\C[C@@H](C(C)=C)CC1=C2C(C([C@@H]([C@@H](C3=C(C=C(C=C3)O)O)O2)O)=O)=C(C(C/C=C(C)\C)=C1O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.