Kuwanon H is a flavonoid isolated from Morus alba that functions as a potent non-peptide antagonist of bombesin receptors. It selectively inhibits the binding of gastrin-releasing peptide to GRP-preferring receptors, exhibiting a Ki value of 290 nM in cellular assays. This compound is valuable for research applications involving cancer biology and neurobiology, particularly in studies focusing on receptor signaling pathways and their role in tumor growth and metastasis.
Kuwanon H is a flavonoid isolated from Morus alba that functions as a potent non-peptide antagonist of bombesin receptors. It selectively inhibits the binding of gastrin-releasing peptide to GRP-preferring receptors, exhibiting a Ki value of 290 nM in cellular assays. This compound is valuable for research applications involving cancer biology and neurobiology, particularly in studies focusing on receptor signaling pathways and their role in tumor growth and metastasis.
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