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KW-3407

Antiarrhythmic Agent

KW-3407 is a potent antiarrhythmic agent that targets various arrhythmogenic stimuli. It effectively inhibits spontaneously occurring arrhythmias induced by two-stage coronary ligation, digitalis, and adrenaline, exhibiting IC50 values of 18.1, 14.4, 18.3, and 21.4 μg/mL, respectively. KW-3407 also decreases sinoatrial node activity and contractile force while enhancing coronary blood flow and atrioventricular conduction times. This compound is valuable for research in cardiovascular pharmacology and the development of antiarrhythmic therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	115750-37-3
Applications	Antiarrhythmic Agent
Formula	C₂₀H₂₇N₃O₂.3/2C₄H₄O₄
Molecular Weight	515.56
SMILES	CCN(CC)CCNC1C2=CC(OC)=CC=C2OCC3=NC=CC=C31.O=C(O)/C=C/C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.