Documents & Downloads

KY-455

ACAT Inhibitor

KY-455 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), effectively targeting various organs including rabbit intestinal, hepatic, macrophage, and adrenal ACAT with IC50 values of 0.4, 0.9, 2.9, and 4.1 μmol/L, respectively. This compound is valuable for research applications related to lipid metabolism and cholesterol homeostasis. Its selective action makes it an important tool in studies aimed at understanding ACAT's role in diseases such as atherosclerosis.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	178469-71-1
Applications	ACAT Inhibitor
Formula	C₂₀H₃₂N₂O
Molecular Weight	316.48
SMILES	O=C(C(C)(C)C)NC1=C(C)C=C(C)C2=C1N(CCCCC)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.