Fig. 1 · Structure

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KY19334

CXXC5-DVL Inhibitor

KY19334 is a CXXC5-DVL inhibitor that activates the Wnt/β-catenin signaling pathway by disrupting the CXXC5-DVL interaction. This compound demonstrates significant biological activity by inhibiting CDK1, leading to reduced proliferation, migration, invasion, and transformation of cancer cells. Additionally, KY19334 promotes wound healing and offers regenerative effects. Its applications extend to research in cancer, inflammation, metabolic disorders, and neurological diseases, including cutaneous squamous cell carcinoma and diabetes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2319609-67-9
Applications CXXC5-DVL Inhibitor
Formula C17H13N3O3
Molecular Weight 307.30
SMILES
O=C(NC1=C/2C=C(OC)C=C1)C2=C3NC4=CC=CC=C4C/3=N\O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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