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KYS-1

Catalog No.: A39825
peptides
KYS-1 is a selective substrate for cathepsin E, exhibiting a Km value of 1.9 μM. This compound is optimized for use in studies involving cathepsin E activity, particularly at an optimal pH of approximately 4.0. KYS-1 is valuable for investigating the role of cathepsin E in various biological processes and can aid in enzyme kinetics studies and therapeutic research involving proteolytic pathways.
KYS-1 592544-81-5 peptides
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Size Price Stock Qty
1mg
$105.00
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5mg
$260.00
In stock
10mg
$405.00
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKYS-1 is a selective substrate for cathepsin E, exhibiting a Km value of 1.9 μM. This compound is optimized for use in studies involving cathepsin E activity, particularly at an optimal pH of approximately 4.0. KYS-1 is valuable for investigating the role of cathepsin E in various biological processes and can aid in enzyme kinetics studies and therapeutic research involving proteolytic pathways.
Product Information
Catalog NumA39825
FormulaC61H82N16O18
Molecular Weight1327.40
CAS Number592544-81-5
Sequence{Mca}-Gly-Ser-Pro-Ala-Phe-Leu-Ala-{Lys(Dnp)}-{d-Arg}-NH2
Sequence shortening{Mca}-GSPAFLA-{Lys(Dnp)}-{d-Arg}-NH2
SMILESC(C(NCC(N[C@H](C(=O)N1[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(=N)N)C(N)=O)=O)CCCCNC3=C(N(=O)=O)C=C(N(=O)=O)C=C3)=O)C)=O)CC(C)C)=O)=O)C)=O)CCC1)CO)=O)=O)C=4C=5C(=CC(OC)=CC5)OC(=O)C4
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