Fig. 1 · Structure

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L-157012

HMGCR Inhibitor

L-157012 is a selective inhibitor of HMG-CoA reductase (HMGCR), a key enzyme involved in the cholesterol biosynthesis pathway. It effectively reduces cholesterol levels and demonstrates significant potential for research applications in studying lipid metabolism and cardiovascular disease. Its mechanism of action makes it a valuable tool for investigating HMGCR-related biological processes and therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 114801-28-4
Applications HMGCR Inhibitor
Formula C24H36O6
Molecular Weight 420.54
SMILES
CC[C@H](C)C(O[C@H]1C[C@@H](C=C2C=C[C@@H]([C@@H]([C@@]12[H])CC[C@@]3([H])OC(C[C@H](O)C3)=O)C)CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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