Fig. 1 · Structure
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L-158809
AT1 Receptor Antagonist
L-158809 is an angiotensin type 1 (AT1) receptor antagonist that exhibits neuroprotective properties against cognitive impairment induced by fractionated whole-brain irradiation. This compound serves as a valuable tool in the study of brain tumor-related pathologies and offers potential for therapeutic exploration in neurodegenerative conditions associated with radiation exposure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 133240-46-7 |
| Applications | AT1 Receptor Antagonist |
| Formula | C24H23N7 |
| Molecular Weight | 409.49 |
| SMILES | CCC1=NC2=C(C)C=C(C)N=C2N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.