Fig. 1 · Structure
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L-162313
Angiotensin II AT1 and AT2 Receptor Agonist
L-162313 is a non-peptide agonist of the angiotensin II AT1 and AT2 receptors, exhibiting IC50 values of 1.1 nM and 2.0 nM, respectively. This compound is instrumental in studies related to vasoconstriction, aldosterone secretion, and cardiovascular hypertrophy. Its potent receptor activity makes it a valuable tool for investigating the cardiovascular system and associated pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 151488-11-8 |
| Applications | Angiotensin II AT1 and AT2 Receptor Agonist |
| Formula | C30H38N4O4S2 |
| Molecular Weight | 582.78 |
| SMILES | O=C(NS(=O)(C1=C(C2=CC=C(CN3C4=NC(C)=CC(C)=C4N=C3CC)C=C2)C=C(CC(C)C)S1)=O)OCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.