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L-163007

AT1/2 Antagonist

L-163007 is an orally active antagonist of both AT1 and AT2 receptors, which are key mediators in the renin-angiotensin system. This compound demonstrates significant potential in the study of cardiovascular diseases, particularly hypertension, by modulating vascular tone and influencing blood pressure regulation. Research applications include the exploration of its effects on cardiovascular function and their implications in related pathophysiological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	1026784-27-9
Applications	AT1/2 Antagonist
Formula	C₃₀H₃₀F₃N₅O₆S
Molecular Weight	645.65
SMILES	O=C(O)NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CCCC)=NN(C4=CC(NC(CC)=O)=CC=C4C(F)(F)F)C3=O)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.