Fig. 1 · Structure

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L-163017

AT Antagonist

L-163017 is a potent, orally active nonpeptide antagonist of the angiotensin II receptor (AT). This compound effectively inhibits the pressor response to angiotensin II, leading to a reduction in blood pressure. L-163017 is primarily utilized in research related to cardiovascular diseases, including hypertension, offering insights into therapeutic approaches for managing these conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 169281-98-5
Applications AT Antagonist
Formula C36H39N5O5S
Molecular Weight 653.79
SMILES
O=C(OCCC(C)C)NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CCC)=NC4=C(C)C(NC(C5=CC=CC=C5)=O)=CN=C43)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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