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L 377202

PDC

L 377202 is a peptide-drug conjugate (PDC) that targets prostate cancer cells via a prostate-specific antigen (PSA)-hydrolyzable peptide linked to Doxorubicin. This compound exhibits potent inhibitory effects on PSA-secreting prostate cancer cells, providing a valuable tool for investigating mechanisms of tumor growth and survival. L 377202 is relevant for research applications focused on prostate cancer therapeutics and the development of targeted delivery systems.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	207395-85-5
Applications	PDC
Formula	C₆₅H₈₉N₉O₂₅
Molecular Weight	1396.45
SMILES	OC1=C2C([C@H](C[C@@](C(CO)=O)(O)C2)O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](C4CCCCC4)NC([C@H](CO)NC([C@H](C)NC([C@H]5N(C[C@H](O)C5)C(CCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=C(O)C6=C1C(C7=CC=CC(OC)=C7C6=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.