Fig. 1 · Structure
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L-645151
Carbonic Anhydrase Inhibitor
L-645151 is a carbonic anhydrase inhibitor that demonstrates significant ocular penetration and hypotensive activity. This compound effectively reduces elevated intraocular pressure (IOP) in o-chymotripsinized rabbit eyes, making it a valuable tool for research into ocular hypotensive agents. Its mechanism supports investigations aimed at treating conditions associated with increased IOP.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 86394-94-7 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C12H14N2O4S2 |
| Molecular Weight | 314.38 |
| SMILES | CC(C)(C(OC1=CC=C2N=C(SC2=C1)S(=O)(N)=O)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.