L 646462

Catalog No.: A29357
5-HT Antagonist
L 646462 is a selective antagonist of serotonin (5-HT) receptors, primarily targeting the peripheral nervous system. With a central/peripheral activity ratio of 143, it is particularly suitable for research into nausea and vomiting, as well as associated neurological disorders. This compound enables the investigation of mechanisms underlying serotonin-related pathologies and the development of therapeutics aimed at these conditions.
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL 646462 is a selective antagonist of serotonin (5-HT) receptors, primarily targeting the peripheral nervous system. With a central/peripheral activity ratio of 143, it is particularly suitable for research into nausea and vomiting, as well as associated neurological disorders. This compound enables the investigation of mechanisms underlying serotonin-related pathologies and the development of therapeutics aimed at these conditions.
Product Information
Catalog NumA29357
FormulaC27H27N3O4
Molecular Weight457.52
CAS Number89149-85-9
SMILESO=C(C1=CC=C2C(/C(C3=CC=CC=C3C=C2)=C4CCN(C)CC/4)=C1)OCN(C(N(C)C5)=O)C5=O
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