Fig. 1 · Structure

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L-657743

α2-Adrenoceptor Antagonist

L-657743 is a potent and selective α2-adrenoceptor antagonist with oral bioavailability. It plays a significant role in modulating neurotransmitter release and can be utilized in studies investigating neurological disorders, particularly depression. This compound's specific action on α2-adrenoceptors makes it a valuable tool for research into the therapeutic potential for managing mood and anxiety-related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 111466-41-2
Applications α2-Adrenoceptor Antagonist
Formula C20H25N3O2
Molecular Weight 339.43
SMILES
O=C1N(C)[C@]2(CCN1C)CCN3CCC4=C(OC5=CC=CC=C54)[C@]3([H])C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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