Fig. 1 · Structure
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L 659286
Elastase Inhibitor
L 659286 is a potent inhibitor of human polymorphonuclear leukocyte elastase (PMN elastase), with a reported Ki of 0.4 μM. This compound is utilized in research to investigate the role of elastase in lung injury mechanisms, particularly through its effects observed in model systems such as hamsters after intratracheal administration. Its specificity and efficacy make it a valuable tool for studying elastase-related pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 119742-06-2 |
| Applications | Elastase Inhibitor |
| Formula | C17H21N5O7S2 |
| Molecular Weight | 471.51 |
| SMILES | O=C(C(N1C2=O)=C(CS([C@@]1([C@H]2OC)[H])(=O)=O)CSC(N(NC3=O)C)=NC3=O)N4CCCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.