Fig. 1 · Structure

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L-685487

13-desmethyl Derivative of FK506

L-685487 is a 13-desmethyl derivative of FK506 that serves as an immunomodulator. This compound demonstrates significant biological activity in regulating immune responses, making it a valuable tool for research in immunology and transplant biology. Researchers can utilize L-685487 to explore mechanisms of immune modulation and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 132055-38-0
Applications 13-desmethyl Derivative of FK506
Formula C42H67NO12
Molecular Weight 777.98
SMILES
O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@@](O2)([H])[C@H](O)[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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