L-701252 is a potent antagonist of the glycine site on the NMDA receptor, exhibiting an IC50 of 420 nM. This compound has demonstrated neuroprotective effects in models of global cerebral ischemia, making it a valuable tool for research into neurodegenerative diseases and excitotoxicity. Its efficacy in modulating NMDA receptor activity positions L-701252 as a promising candidate for studies focused on synaptic transmission and neurological disorders.
L-701252 is a potent antagonist of the glycine site on the NMDA receptor, exhibiting an IC50 of 420 nM. This compound has demonstrated neuroprotective effects in models of global cerebral ischemia, making it a valuable tool for research into neurodegenerative diseases and excitotoxicity. Its efficacy in modulating NMDA receptor activity positions L-701252 as a promising candidate for studies focused on synaptic transmission and neurological disorders.
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