Fig. 1 · Structure
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L-750667
Dopamine D4 Receptor Antagonist Ligand
L-750667 is a selective antagonist of the dopamine D4 receptor. This compound has been shown to specifically bind to dopamine D4 receptors in the rat retina, exhibiting a Kd value of 0.06 nM. L-750667 plays a significant role in the regulation of the light-sensitive cAMP pool, making it a valuable tool for studying dopamine signaling pathways and their implications in neurobiology and vision research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 158985-08-1 |
| Applications | Dopamine D4 Receptor Antagonist Ligand |
| Formula | C18H19IN4 |
| Molecular Weight | 418.27 |
| SMILES | IC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.