Fig. 1 · Structure

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L-768673

IKs Blocker

L-768673 is a potent selective blocker of the IKs ion channel, exhibiting significant antiarrhythmic properties. It influences both atrial and ventricular refractoriness and affects pacemaker activity in cardiac tissue. This compound is valuable for research into arrhythmias and their underlying mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Blocker
CAS Number 177954-68-6
Applications IKs Blocker
Formula C27H18F9N3O2
Molecular Weight 587.44
SMILES
O=C(CC1=CC=C(C=C1C(F)(F)F)C(F)(F)F)N[C@H]2C(N(C3=CC=CC=C3C(C4=CC=CC=C4)=N2)CC(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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