L-772405 is a selective agonist for the 5-HT1D receptor, demonstrating Ki values of 318 nM and 29 nM against guinea pig 5-HT1B and 5-HT1D receptors, respectively, while exhibiting a Ki value greater than 1000 nM for the rat 5-HT transporter. This compound effectively reduces potassium-induced serotonin (5-HT) release, with an IC50 of 240 nM. L-772405 is valuable in exploring serotonergic signaling and could serve as a useful tool in studies of mood disorders and other neurological research applications.
L-772405 is a selective agonist for the 5-HT1D receptor, demonstrating Ki values of 318 nM and 29 nM against guinea pig 5-HT1B and 5-HT1D receptors, respectively, while exhibiting a Ki value greater than 1000 nM for the rat 5-HT transporter. This compound effectively reduces potassium-induced serotonin (5-HT) release, with an IC50 of 240 nM. L-772405 is valuable in exploring serotonergic signaling and could serve as a useful tool in studies of mood disorders and other neurological research applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
