Fig. 1 · Structure
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L-AP3
mGluR Antagonist
L-AP3 is a selective antagonist of metabotropic glutamate receptors (mGluRs). It demonstrates inhibitory activity against D-phosphoserine and L-phosphoserine, with IC50 values of 368 μM and 2087 μM, respectively. This compound is valuable for research applications focusing on the modulation of glutamatergic signaling and its implications in various neurological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 23052-80-4 |
| Applications | mGluR Antagonist |
| Formula | C3H8NO5P |
| Molecular Weight | 169.07 |
| Synonyms | 3-Phosphono-L-alanine |
| SMILES | N[C@@H](CP(O)(O)=O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.