Fig. 1 · Structure

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L-AP4 monohydrate

mGluR III Agonist

L-AP4 monohydrate is a selective agonist of group III metabotropic glutamate receptors (mGluR), demonstrating EC50 values of 0.13 μM for mGlu4, 0.29 μM for mGlu8, 1.0 μM for mGlu6, and 249 μM for mGlu7. Its potent activity makes L-AP4 a valuable tool for investigating the physiological roles of mGluR III in various neurological processes. This compound is widely used in research focused on synaptic modulation and potential therapeutic applications for neuropsychiatric disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2247534-79-6
Applications mGluR III Agonist
Formula C4H12NO6P
Molecular Weight 201.11
Synonyms L-APB monohydrate
SMILES
O=C(O)[C@@H](N)CCP(O)(O)=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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