Fig. 1 · Structure
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L-Asparagine-1,2,3,4-13C4 monohydrate
Stable Isotope
L-Asparagine-1,2,3,4-13C4 monohydrate is a stable isotope-labeled form of the amino acid L-asparagine. This compound serves as a substrate for L-asparaginase, an enzyme critical in the treatment of leukemia, which depletes asparagine and glutamine levels to inhibit protein biosynthesis and promote apoptosis in lymphoblasts. L-Asparagine-1,2,3,4-13C4 monohydrate has applications in research involving acute lymphoblastic leukemia, functioning as a biomarker and enabling detailed studies of metabolic pathways related to cancer cell growth and survival.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 768348-44-3 |
| Applications | Stable Isotope |
| Formula | 13C4H8N2O3 |
| Molecular Weight | 136.09 |
| SMILES | N[13C]([13CH2][13C@H](N)[13C](O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.