L-Asparagine-4-13C monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine. This compound serves as an essential substrate for L-Asparaginase, an enzyme utilized in the treatment of leukemia due to its ability to deplete asparagine, thereby inhibiting RNA and DNA synthesis in lymphoblasts and inducing apoptosis. L-Asparagine-4-13C monohydrate is valuable in research applications, including its use as a biomarker for investigating childhood acute lymphoblastic leukemia and studying metabolic pathways in cancer cells with low asparagine synthetase expression.
L-Asparagine-4-13C monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine. This compound serves as an essential substrate for L-Asparaginase, an enzyme utilized in the treatment of leukemia due to its ability to deplete asparagine, thereby inhibiting RNA and DNA synthesis in lymphoblasts and inducing apoptosis. L-Asparagine-4-13C monohydrate is valuable in research applications, including its use as a biomarker for investigating childhood acute lymphoblastic leukemia and studying metabolic pathways in cancer cells with low asparagine synthetase expression.
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