Fig. 1 · Structure
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L-Asparagine-4-13C monohydrate
Stable Isotope
L-Asparagine-4-13C monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine. This compound serves as an essential substrate for L-Asparaginase, an enzyme utilized in the treatment of leukemia due to its ability to deplete asparagine, thereby inhibiting RNA and DNA synthesis in lymphoblasts and inducing apoptosis. L-Asparagine-4-13C monohydrate is valuable in research applications, including its use as a biomarker for investigating childhood acute lymphoblastic leukemia and studying metabolic pathways in cancer cells with low asparagine synthetase expression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 286437-12-5 |
| Applications | Stable Isotope |
| Formula | C313CH10N2O4 |
| Molecular Weight | 151.13 |
| Synonyms | (-)-Asparagine-4-13C monohydrate; Asn-4-13C monohydrate; Asparamide-4-13C monohydrate |
| SMILES | N[13C](C[C@H](N)C(O)=O)=O.[H]O[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.