Fig. 1 · Structure
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L-Aspartyl-L-phenylalanine
ACE Inhibitor
L-Aspartyl-L-phenylalanine is an angiotensin-converting enzyme (ACE) inhibitor with a Ki of 11 μM, derived from the metabolic breakdown of aspartame. This compound demonstrates significant inhibitory activity towards ACE, making it a valuable tool for research in cardiovascular diseases and hypertension. Its ability to modulate ACE activity allows for investigations into regulatory mechanisms and therapeutic potentials in related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 13433-09-5 |
| Applications | ACE Inhibitor |
| Formula | C13H16N2O5 |
| Molecular Weight | 280.28 |
| SMILES | OC(C[C@H](N)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.