Fig. 1 · Structure
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L-threo-PPMP
GlcT Inhibitor
L-threo-PPMP is a selective inhibitor of UDP-Glc: Ceramide β1,1-glucosyltransferase (GlcT), targeting glycosphingolipid biosynthesis. This compound effectively induces apoptosis in cancer cells, demonstrating significant anti-cancer activity. L-threo-PPMP is valuable for research applications focused on cancer biology and the role of glycosphingolipids in tumor progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 207278-87-3 |
| Applications | GlcT Inhibitor |
| Formula | C29H50N2O3 |
| Molecular Weight | 474.72 |
| SMILES | CCCCCCCCCCCCCCCC(N[C@@H](CN1CCOCC1)[C@@H](O)C2=CC=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.