Fig. 1 · Structure
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L-Thyroxine sodium salt pentahydrate
Thyroid Hormone
L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine or T4, acts as a synthetic thyroid hormone primarily targeting thyroid hormone receptors. It plays a critical role in the research of hypothyroidism and metabolic functions. The compound is utilized to study the conversion of T4 to the biologically active form, triiodothyronine (T3), mediated by deiodinase enzymes. Its application extends to various experimental settings assessing thyroid hormone regulation and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6106-07-6 |
| Applications | Thyroid Hormone |
| Formula | C15H20I4NNaO9 |
| Molecular Weight | 888.93 |
| Synonyms | Sodium levothyroxine pentahydrate |
| SMILES | N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O.O.O.O.O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.