Fig. 1 · Structure
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L694247
5-HT1D Agonist
L694247 is a selective agonist of the 5-HT1D receptor, exhibiting high affinity with a pIC50 value of 10.03. It shows lower potency against other serotonin receptors, with pIC50 values of 8.64 for 5-HT1A, 6.42 for 5-HT1C, and 5.66 for 5-HT1E. This compound is valuable for research applications focusing on serotonergic signaling and its implications in neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 137403-12-4 |
| Applications | 5-HT1D Agonist |
| Formula | C20H21N5O3S |
| Molecular Weight | 411.48 |
| SMILES | CS(=O)(NC1=CC=C(CC2=NOC(C3=CC4=C(NC=C4CCN)C=C3)=N2)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.