L694247

Catalog No.: A46032
5-HT1D Agonist
L694247 is a selective agonist of the 5-HT1D receptor, exhibiting high affinity with a pIC50 value of 10.03. It shows lower potency against other serotonin receptors, with pIC50 values of 8.64 for 5-HT1A, 6.42 for 5-HT1C, and 5.66 for 5-HT1E. This compound is valuable for research applications focusing on serotonergic signaling and its implications in neurological disorders.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$215.00
In stock
10mg
$370.00
In stock
25mg
$655.00
In stock
50mg
$895.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL694247 is a selective agonist of the 5-HT1D receptor, exhibiting high affinity with a pIC50 value of 10.03. It shows lower potency against other serotonin receptors, with pIC50 values of 8.64 for 5-HT1A, 6.42 for 5-HT1C, and 5.66 for 5-HT1E. This compound is valuable for research applications focusing on serotonergic signaling and its implications in neurological disorders.
Product Information
Catalog NumA46032
FormulaC20H21N5O3S
Molecular Weight411.48
CAS Number137403-12-4
SMILESCS(=O)(NC1=CC=C(CC2=NOC(C3=CC4=C(NC=C4CCN)C=C3)=N2)C=C1)=O
Useful Calculator

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