Fig. 1 · Structure

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L759633

CB2 Agonist

L759633 is a selective agonist of the cannabinoid receptor type 2 (CB2), demonstrating a Ki value of 6.4 nM for CB2 and 1043 nM for CB1, highlighting its potency and selectivity. This compound inhibits Forskolin-stimulated cAMP production, making it a valuable tool for investigating CB2 receptor signaling pathways. L759633 holds significant potential for research applications in areas such as immunology and neurobiology, where modulation of the endocannabinoid system may provide therapeutic insights.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 174627-50-0
Applications CB2 Agonist
Formula C26H40O2
Molecular Weight 384.59
SMILES
COC1=C2[C@@]3([H])[C@](CC=C(C)C3)([H])C(C)(C)OC2=CC(C(C)(C)CCCCCC)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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