LA-419 is an orally active nitric oxide (NO) donor that effectively reduces fecal worm egg excretion and shortens the duration of egg shedding in mice infected with S. venezuelensis. Additionally, it decreases the larval load in the lungs and the count of parasitic females in the intestines. LA-419 also demonstrates protective effects against atherosclerosis in apolipoprotein E-deficient mice, making it valuable for studies in infection and cardiovascular diseases.
LA-419 is an orally active nitric oxide (NO) donor that effectively reduces fecal worm egg excretion and shortens the duration of egg shedding in mice infected with S. venezuelensis. Additionally, it decreases the larval load in the lungs and the count of parasitic females in the intestines. LA-419 also demonstrates protective effects against atherosclerosis in apolipoprotein E-deficient mice, making it valuable for studies in infection and cardiovascular diseases.
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